WebFeb 19, 2024 · Clotrimazole can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC … WebThe invention discloses clotrimazole cream and a preparation method thereof. The clotrimazole cream comprises components in percentage by mass as follows: 1% of clotrimazole, 17%-34% of oleaginous bases, 4%-6% of an emulsifying agent, 5%-10% of a moisturizer, 1.1%-3% of a preservative, 0.03%-0.05% of a complexing agent and the …
Development and validation of stability indicating HPLC method …
WebMar 7, 2024 · The new HPLC method showed high specificity and the robustness was less than 1% RSD (Tables 5 and 6). The method also demonstrated ... “Development and validation of HPTLC assay method for simultaneous quantification of hydrocortisone and clotrimazole in cream and applying for stability indicating test,” Journal of the Chilean ... WebJul 4, 2008 · Various analytical methods have been reported for the estimation of clotrimazole that include HPLC [2-8], UV/Vis spectrophotometric [9-13], colorimetric , differential pulse polarographic . … ray wingert
A NEW STEBILITY INDICATING RP-HPLC-PDA METHOD FOR …
WebThe proposed HPLC method provide simple, accurate and reproducible quantitative analysis for determination of PNZ and LID and in tablet. The method was validated as per ICH guidelines. ... Development and Validation of Advance Simultaneous Equation Methods for Lidocaine Hydrochloride and Clotrimazole in Ear DropAsian J Pharm Res201552108 … Webnone of the reported methods describes a simple HPLC method for estimation of clotrimazole in gelatin film for-mulation. Furthermore, buffers were used in the mobile phase of reported HPLC methods. Thus, there was a need for a validated simple HPLC method to determine clotrimazole in gelatin film formulation without any pre-treatment … WebSep 6, 2016 · A simple, reliable HPLC method was developed and validated for quantitation of clotrimazole in human plasma. Preparation was carried out using protein precipitation … ray windsor