2024 Early endosome antigen 1

Early endosome antigen 1

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August undefined, 2024

WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. … WebMar 5, 2024 · EEA1 early endosome antigen 1 [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & …

Anti-EEA1 Antibody - Sigma-Aldrich

WebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early … WebMar 3, 2015 · To investigate whether GALNT1 regulates EGFR trafficking, immunofluorescence staining of GALNT1 knockdown HA22T and PLC5 cells treated with EGF 10 ng/ml was performed to analyze for co-localization of EGFR (red) with early endosome antigen 1 (EEA1) (green) or lysosomal associated membrane protein 1 … catalina tekken

Lecture 4.6 Antigen processing.pdf - Learning goals Antigen...

WebThe endocytic vesicles mature to early endosomes and then the late endosomes by inward budding of the plasma membrane. The late endosomes turn into MVBs by accumulating the intraluminal vesicles ... Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. Eur J Immunol 2003; … WebNov 29, 2016 · Early endosome antigen-1 and Ras-related protein-11 expressions were upregulated; however, the localized distributions of these pivotal proteins were altered. We hypothesized that these LVLS were held by the internalized and dispersed particles decreasing the amount of cell membrane available to support the completion of cytokinesis. Web3 hours ago · Our studies found that CRB3 could colocalize with EEA1-positive early endosomes, CD63-positive late endosomes and Rab11-positive recycling endosomes . In addition, after 2 hours of ... sequentially. Then, antigen retrieval was performed in Tris-EDTA buffer (pH 9.0) heated to 95°C for 20 min. Endogenous peroxidase activity was … catalina vallejos y su hija

Endocytic recycling Nature Reviews Molecular Cell …

NeuroMab™ anti-Human Early Endosome Antigen 1 (EEA1) IgG …

WebSep 16, 2016 · Popular answers (1) The original characterization of "Early Endosomes" is defined by those compartments labeled by transferrin after 20 to 30 minutes of addition. EEA1 (early endosome antigen 1 ... WebJan 3, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast … catalina skin instituteWebEarly endosome antigen 1 (EEA1) is a 170 kDa coiled-coil protein belonging to a group of early endosomal Rab5 effector proteins. EEA1 has a putative role in the tethering/docking of endocytic vesicles prior to their fusion with early endosomes. This protein is characterized as containing a zinc finger-like domain and coiled-coil regions. catalog jotun 2022

"WebThe FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization. Lawe DC, Patki V, Heller-Harrison … " - Early endosome antigen 1

Early endosome antigen 1

WebSep 17, 2024 · The crucial effectors of Rab5 are early endosome antigen-1 (EEA1) [28, 29], rabaptin-5 [30, 31, 37], rabenosyn-5 [32, 38], APPL1/2 [33, 34], and ZFYVE21 (Table 1). EEA1, a key effector of Rab5 with a molecular weight of 162 kD, is a biomarker for early endosomes and has a parallel coiled-coil homodimer structure. WebEndosomes are found in three forms: early endosomes, late endosomes, and recycling endosomes. The early endosomes develop into late endosomes, which then fuse with …

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WebEarly endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like ... WebThank you for your interest in NeuroMab™ anti-Human Early Endosome Antigen 1 (EEA1) IgG fraction Antibody. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebJan 30, 2012 · Depletion of Rabenosyn-5, but not of other early endosomal proteins such as early endosome antigen 1, resulted in impaired transferrin uptake and lysosomal degradation of transferrin receptors. These studies reveal a critical role for Rabenosyn-5 in determining the fate of transferrin receptors internalized by clathrin-mediated endocytosis …

WebJul 9, 2024 · The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: … WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. Synonyms MST105, MSTP105, ZFYVE2 Links HGNC:3185. NCBI Gene ID: 8411. neXtProt AC: NX_Q15075. UniProt: Q15075. Chr Location ...

WebOct 1, 2013 · Early endosome antigen 1 (EEA1) is a peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence staining of EEA1 in macrophage cells yields punctuate staining pattern consistent with the cytoplasmic distribution of endosomes, but in a different way when compare uninfected-macrophages ( Fig. 2A ) in …

WebEea1 early endosome antigen 1 [ (house mouse)] Gene ID: 216238, updated on 8-Nov-2024 Summary Predicted to enable 1-phosphatidylinositol binding activity; GTP … catalogo jost onlineWebEarly Endosome Antigen 1. In the case of the EEA1 FYVE domain, the emission of a single conserved tryptophan residue located in the head group binding site is quenched … catalog jotun paintWebJan 17, 2024 · the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1; F. tularensis-containing endosomes associated with early endosome antigen 1 (EEA1) followed by lysosome-associated membrane protein 1 (LAMP-1), with … catalogo skillus joyeriaWebEEA1 Antibodies. Antibodies that detect EEA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … catalina rain jacketWebEEA1 early endosome antigen 1 [ (human)] Gene ID: 8411, updated on 8-Jan-2024 Summary Enables 1-phosphatidylinositol binding activity; GTP-dependent protein binding … catalogo valvula kuhnkeWebJul 9, 2024 · The purified cDNA (MS-5.1) was characterized by a poly A tail and an open reading frame that encoded 1329 amino acids. The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: Antibodies from rabbits immunized with the recombinant … catalogo vulkoWebFeb 4, 2000 · Early endosome antigen 1 (EEA1) is 170-kDa polypeptide required for endosome fusion. EEA1 binds to both phosphtidylinositol 3-phosphate (PtdIns3P) and to … catalogo jost on line