Kashin beck disease gwas
Webb9 okt. 2014 · Kashin-Beck disease (KBD) is a chronic osteochondropathy, the pathogenesis of which remains elusive. The aim of this study was to identify … Webb21 feb. 2024 · In Proceedings of the international workshop on kashin-beck disease and non-communicable diseases Vol. 74 96–101 (World Health Organization, Geneva, 1990).
Kashin beck disease gwas
Did you know?
Webb7 maj 2024 · Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy, which manifests as joint deformities and growth retardation ... In an independent GWAS, Wu et al. identified two common variants rs718314 and rs1049380 in ITPR2 gene as novel susceptibility loci for renal cell carcinoma (RCC; Wu et al., 2012). Kashin–Beck disease (KBD) is a chronic, endemic type of osteochondropathy (disease of the bone) that is mainly distributed from northeastern to southwestern China, including 15 provinces. As of 2011, Tibet has the highest incidence rate of KBD in China. Southeast Siberia and North Korea are other affected areas. KBD usually involves children ages 5–15. To date, more than a million individuals have had KBD. The symptoms of KBD include joint pain, morning stiffness in the join…
WebbDisabling osteochondrodysplasia with osteosclerosis, cone-shaped metaphysis, and shortening of the diaphysis. It is endemic in parts of Siberia and northern China. … Webb3 maj 2024 · Kashin-Beck Disease (KBD) is a type of endemic, chronic, and disabling osteoarthropathy with high disability. KBD is also named as endemic …
Webb7 apr. 2016 · Kashin-Beck disease ... (2+) channel in the skeletal muscle, have been reported to correlate with CV diseases. We performed the first GWAS for ECG-LVH, implicating the skeletal muscle Ca ... Webb7 maj 2024 · Abstract Background Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy. Inositol 1,4,5‐triphosphate receptor type 2 ... In an independent GWAS, Wu et al. identified two common variants rs718314 and rs1049380 in ITPR2 gene as novel susceptibility loci for renal cell carcinoma (RCC; Wu et al., 2012).
Webb13 okt. 2015 · Kashin-Beck disease (KBD) is a chronic osteochondropathy [1, 2], which is prevalent at some areas of China, Russia, and North Korea. KBD is a complex …
Webb13 okt. 2015 · GWAS meta-analysis identified six candidate genes with pleiotropic effects, including PDGFD, SOX5, DPYD, CTR9, SPP1, and COL4A1. GO analysis identified 16 significant GO shared by KBD and the... stores to get credit cardsWebb9 juli 2012 · Kashin–Beck disease (KBD) is characterized by chondrocytic necrosis and apoptosis, cartilage degeneration and matrix degradation ... miRNA–mRNA target databases, GWAS databases, KEGG and so on. IPA is easy to operate and offers high-quality diagrams of pathways and networks that contain much information using a visual … roses chickenWebb11 okt. 2016 · Recent study observed defective autophagy in chondrocytes with Kashin–Beck Disease (KBD). To clarify the potential role of autophagy-related ATG4C gene in the development of KBD, we conducted an integrative analysis of genetic association, messenger ribonucleic acid (mRNA) and protein expression of ATG4C in … roses chicken kievWebb6 apr. 2024 · The mission of the Public Health Genomics is to integrate advances in human genetics into public health research, policy, and programs stores to get backpacksWebb20 aug. 2015 · Kashin-Beck Disease (KBD) is a chronic disabling osteochondropathy (Stone 2009). The primary clinical manifestations of KBD include pain, limited motion, … stores to get graphic teesWebbThis study aims to uncover insight into the epigenetic modifications for Kashin-Beck disease (KBD) by integrating genome-wide association studies (GWAS), … roses chicago peaceWebb15 dec. 2014 · Kashin–Beck disease (KBD) is a serious osteoarthropathia, mainly characterized by excessive chondrocyte necrosis and apoptosis. The molecular … stores to get free stuff on your birthday