Klf2 colon
WebSep 24, 2013 · KLF2, KLF3, KLF4, KLF11, KLF13, KLF14, KLF15 and KLF16 all inhibit cell growth and transformation mediated by oncogenic KRAS 85. However, in mouse embryonic fibroblasts lacking p21, KLF4 bypasses... WebKLF2 is altered in 1.02% of all cancers with colon adenocarcinoma, lung adenocarcinoma, bladder urothelial carcinoma, breast invasive ductal carcinoma, and pancreatic …
Klf2 colon
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WebJan 17, 2024 · KLF2 is critical to maintaining endothelial barrier integrity and preventing gap formations and in prevention of glomerular endothelial cell and podocyte damage in diabetic mice. KLF4 is renoprotective in the setting of AKI and is a critical regulator of proteinuria in mice and humans. WebNov 18, 2024 · KLF2 regulates metaflammation transcription in macrophages RNA-sequencing of bone marrow-derived macrophages (BMDMs) isolated from myeloid-specific KLF2 knockout (K2KO) and control (LysM) mice...
WebMar 1, 2024 · For example, KLF2 inhibited the proliferation of colon cancer cells with the p53 mutation by inducing the expression of p21 [13]. Additionally, SNHG3 facilitated the malignant progression of glioma by epigenetically repressing KLF2 and p21 by recruiting enhancer of zeste homolog 2 to the promoter of KLF2 and p21 [14]. Based on these ... WebKLF2 Antibody (PA5-115479) in IHC (P) Immunohistochemistry analysis of KLF2 in human colorectal cancer and adjacent normal tissues. Samples were treated with formaldehyde …
WebMar 19, 2024 · In colon cancer and rectal cancer, KLFs were also shown to be associated with a variety of immune cells. ... in CRC patients, we used various online analytic tools, including ONCOMINE, TCGA, cBioPortal, and the TIMER database. KLF2-6, KLF8-10, KLF12-15, and KLF17 mRNA expression levels were dramatically downregulated in CRC tissues, … WebOct 17, 2024 · Marginal zone lymphoma (MZL) is classified as a group of slow-growing, non-Hodgkin’s B-cell lymphomas. 1. Extranodal marginal zone B-cell lymphoma or mucosa-associated lymphoid tissue (MALT ...
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WebApr 8, 2024 · In colon cells, CDX2 upregulated KLF4 by binding to KLF4 promoter and reducing the association of histone 3 lysine 4 trimethylation with KDM5B demethylase, and acting as a tumor suppressor. dick lovett bmw carsWebMar 3, 2024 · MAP3K2 is a serine/threonine kinase belonging to the MAP3K superfamily 11. To investigate the role of MAP3K2 in the intestine, we added dextran sodium sulfate (DSS), which causes colitis, to the... dick lovett bmw useddick lovett bmw used carsWebApr 1, 2024 · Introduction. Krüppel-like factor 2 (KLF2), a zinc-finger transcription factor, is a crucial regulator of differentiation, proliferation and activation of various cell types, including T- and B-lymphocytes 1, 2, 3.Within the B cell lineage, KLF2 expression is induced during early B cell development in the bone marrow (BM) by signals of the pre-B cell receptor and … dick lovett body shop swindonWebExpression of KLF2 (LKLF) in colon tissue. Antibody staining with HPA055964 in immunohistochemistry. We use cookies to enhance the usability of our website. If you … dick lovett bmw bodyshop bristolWebKLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription. For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization. Bioinformatics dick lovett bodyshop swindonWebNov 25, 2010 · KLF2 (lung Krüppel-like factor) is expressed in lung, endothelial cells, and lymphocytes. 19–24 KLF2 deficiency is embryonic lethal because of severe hemorrhage resulting from defects in blood vessel integrity. 19 In T-cell biology, KLF2 has been demonstrated to regulate T-cell properties of quiescence, survival, activation, and … dick lovett head office