2024 Synovial fluid and blood immune raman sers

Synovial fluid and blood immune raman sers

Author: tkad

August undefined, 2024

WebThe synovial fluid (SF) samples were placed on ice immediately after collection, centrifuged at 1400 rpm for 10 minutes to remove cells and debris and stored at −80°C. Synovial fluid mononuclear cells were separated on a Ficoll gradient at 2050 rpm for 25 minutes. The cells were washed with PBS and centrifuged twice at 1400 rpm for 10 minutes. WebIn this preliminary study on synovial fluid (SF), knee osteoarthritis (OA) grading of n = 23 patients was accomplished by combining two methods: resonant Raman spectroscopy, …

Synovium & Synovial Fluid - Physiopedia

WebMay 1, 2009 · Raman data of synovial fluid from 37 patients were used in comparing Raman band intensity ratios between low severity (n=14) and high (n=23) severity groups. For N=37, the power was 84%. The power for a comparison of all five K/L groups (0–4) was 62% using an ANOVA, one-way, fixed effect f-test. WebAug 6, 2024 · Surface enhanced Raman scattering research on joint synovial fluid. Abstract: Osteoarthritis (OA) is considered as a chronic disease without obvious symptoms in early … symmetric distribution vs normal distribution

Photodiagnosis using Raman and surface enhanced Raman scattering of …

WebFeb 14, 2024 · Critical comparison between SERS and FTIR methods of analysis reveals that on average the reported sensitivity for biomarkers in biofluids for SERS vs FTIR is about 103 to 105 times higher,... WebNov 1, 2002 · The effects of RA synovial fluids on neutrophil apoptosis were studied in two experimental conditions: (i) spontaneous apoptosis evaluated after 18 h in vitro incubation and (ii) apoptosis of immune complex‐activated neutrophils after 12 h of incubation. WebSep 1, 2005 · The aim of this study was to review works published in Raman scattering and surface enhanced Raman scattering (SERS) on bodily fluids. The main Raman studies have concentrated on the detection of metabolites in the aqueous humour, urine and blood-based fluids and on drugs in the latter. Other bodily fluids are also studied, e.g. vitreous humour. thabile mdletshe

Synovial Fluid - an overview ScienceDirect Topics

Raman spectroscopy for viral diagnostics SpringerLink

WebAug 30, 2024 · The use of Raman spectroscopy combined with saliva is an exciting emerging spectroscopy-biofluid combination. In this review, we summarize current … WebEvidence for the presence of immune complexes in blood, synovial fluid, and tissues of patients with rheumatoid arthritis (RA) includes low complement levels in blood and … symmetric disc bulgeWebMay 1, 2009 · For many years, viscosity has been the primary method used by researchers in rheumatology to assess the physiochemical properties of synovial fluid in both normal and osteoarthritic patients. However, progress has been limited by the lack of methods that provide multiple layers of information, use small sample volumes, and are rapid. Raman … symmetric digital subscriber line

"WebThis fluid is generated from an ultrafiltrate of blood plasma which is regulated by synovium. The purpose of this fluid is to lubricate the cartilage of the bone joint and provide … " - Synovial fluid and blood immune raman sers

Synovial fluid and blood immune raman sers

Emerging Role of Exosomes in the Joint Diseases

WebJun 1, 2024 · Raman spectra of the synovial fluid of the knee joint: I group-without pathology; II groupwith chronic damage of infra-articular structures; III group-the stage 4 … WebMar 31, 2024 · This fluid is called the synovial fluid. This infection usually begins in another area of the body and spreads through the bloodstream to the joint tissue. The infection may also enter the...

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WebNational Center for Biotechnology Information WebAug 17, 2024 · Synovial fluid often displays a high fluorescence response that obscures the Raman signal, like many other complicated biological materials. As a result, only limited Raman methodologies have been used to study this material.

WebJan 7, 2024 · The synovial fluid analysis by using Raman Scattering spectroscopy in order to educe the synovial joint pathology E Timchenko1, P Timchenko1, L Volova2, D … WebAug 1, 2024 · The mean SERS spectra of synovial fluid from the high-grade (red) and low-grade (blue) osteoarthritis (OA) groups as well as their difference spectrum (black). The SERS spectra of the SF were acquired using iodide-modified AgNPs, which were previously shown to selectively amplify the Raman spectra of proteins. 10., 20.

WebJun 1, 2024 · Surface-Enhanced Raman spectroscopy (SERS) provides a reliable way to diagnose typhoid, an infectious disease, due to its high accuracy, sensitivity, and … WebJan 8, 2024 · Exosomes are a subset of small, membrane-bound extracellular vesicles that are important for communication among cells. They originate from the cell membrane during endocytic internalization, and are stable in biological fluids, including blood and synovial fluids. Increasing knowledge is emerging about exosomes in joint diseases, …

WebSynovial Fluid. Synovial fluid (SF) is the viscous liquid in the synovial cavity and is secreted by the synovial membrane. Its function is to reduce friction between the articular …

WebAug 29, 2024 · An ultrasensitive surface-enhanced Raman scattering (SERS) immunoassay based on diatom biosilica with integrated gold nanoparticles (AuNPs) for the detection of interleukin 8 (IL-8) in blood plasma has been developed. thabile meaningWebNov 9, 2024 · A synovial fluid analysis is a group of tests that detect changes in synovial fluid. Synovial fluid is the liquid that surrounds and lubricates joints. When patients have swollen, painful joints, a synovial fluid analysis can give valuable information about the underlying source of the problem. thabile mazolwane all albumsWebMar 28, 2024 · It also tightly participated in immune responses in physiological conditions and lead to sterile inflammation in pathological conditions [2,3]. Specifically, in rheumatoid arthritis (RA) patients, the levels of cfDNA in synovial fluid (SF) and peripheral blood were highly elevated . thabile myeni ageWebSurface-enhanced Raman spectroscopy or surface-enhanced Raman scattering (SERS) is a surface-sensitive technique that enhances Raman scattering by molecules adsorbed on rough metal surfaces or by nanostructures such as plasmonic-magnetic silica nanotubes. The enhancement factor can be as much as 10 10 to 10 11, which means the technique … thabile mthethwaWebMay 11, 2024 · The synovial fluid provides nourishment to the underlying articular cartilage and decreases the adherence of cells and proteins 21,22. The synovial fluid also contains … symmetric double sided two-way ranging symmetric dockingWebApr 10, 2024 · Raman spectroscopy offers the potential for fingerprinting biological molecules at ultra-low concentration and therefore has potential for the detection of viruses. Here we review various Raman techniques employed for the investigation of viruses. Different Raman techniques are discussed including conventional Raman spectroscopy, … thabile myeni new album